Our Research
RECENT ADVANCES IN OUR UNDERSTANDING OF RADIATION EFFECTS
2019年 Our Research (92)～最新 の投稿はこちらからお読みいただけます
(93) Aug 16, 2019
Hitomi Moriyama(Graduate School of Human Health Sciences, Tokyo Metropolitan University / QST, NIRS)
Neutron-Induced Rat Mammary Carcinomas Are Mainly of Luminal Subtype and Have Multiple Copy Number Aberrations
(92) Aug 10, 2019
Mikio Shimada (Tokyo Institute of Technology)
DNA Damage Response After Ionizing Radiation Exposure in Skin Keratinocytes Derived from Human-Induced Pluripotent Stem Cells
2018年 Our Research (85)～(91) の投稿はこちらからお読みいただけます
(91) Oct 6, 2018
Reona KATO (Laboratory of Molecular Radiology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo)
Human Rad52 promotes XPG-mediated R-loop processing to initiate transcription-associated homologous recombination repair
(90) Oct 6, 2018
Masaki NAGANE (Azabu University)
Radiation-induced nitric oxide production accelerates endothelial senescence
(89) Oct 5, 2018
Yoshitaka Matsumoto (Radiation Oncology, Clinical Medicine, Faculty of Medicine, University of Tsukuba, Proton Medical Research Center, University of Tsukuba Hospital)
Antimetastatic Effects of Carbon-Ion Beams on Malignant Melanomas
(88) Oct 4, 2018
Hironori YOSHINO (Hirosaki University Graduate School of Health Sciences)
Effects of retinoic acid-inducible gene-I-like receptors activations and ionizing radiation cotreatment on cytotoxicity against human non-small cell lung cancer in vitro
(87) Oct 4, 2018
Norie KANZAKI (Graduate School of Health Sciences, Okayama University, Ningyo-toge Environmental Engineering Center of the Japan Atomic Energy Agency)
Knowledge Discovery of Suppressive Effect of Disease and Increased Anti-oxidative Function by Low-dose Radiation Using Self-organizing Map
(86) May 30, 2018
Lue Sun (Department of Radiation Biology, Faculty of Medicine, University of Tsukuba, Department of Radiological Health Science, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health)
Dose-dependent decrease in anti-oxidant capacity of whole blood after irradiation: A novel potential marker for biodosimetry
(85) Jan 9, 2018
Mikio Shimada (Laboratory for Advanced Nuclear Energy, Institute of Innovative Research, Tokyo Institute of Technology)
Effect of different dose rates of ionizing radiation of ciliogenesis in hTERT-RPE1 cells
2017年 Our Research (77)～(84) の投稿はこちらからお読みいただけます
(84) Oct 6, 2017
Lue Sun (Department of Radiological Health Science, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health)
Metabolic analysis of radioresistant medulloblastoma stem-like clones and potential therapeutic targets
(83) Oct 5, 2017
Hiroko IKEDA (現所属: Gunma University Initiative for Advanced Research, 発表時の所属: Gunma University Graduate School of Medicine/Gunma University Heavy-ion Medical Center)
A new system for three-dimensional clinostat synchronized X-irradiation with a high-speed shutter for space radiation research
(82) Oct 5, 2017
Hiroko IKEDA (現所属: Gunma University Initiative for Advanced Research, 発表時の所属: Gunma University Graduate School of Medicine/Gunma University Heavy-ion Medical Center)
Development and performance evaluation of a three-dimensional clinostat synchronized heavy-ion irradiation system
(81) July 28, 2017
Huizi Keiko Li (Research Fellow of Japan Society for the Promotion of Science / Graduate School of Medical and Pharmaceutical Sciences, Chiba University)
Locoregional therapy with α-emitting trastuzumab against peritoneal metastasis of human epidermal growth factor receptor 2-positive gastric cancer in mice
(80) June 15, 2017
Huizi Keiko Li (Research Fellow of Japan Society for the Promotion of Science / Graduate School of Medical and Pharmaceutical Sciences, Chiba University)
PU-H71, a novel Hsp90 inhibitor, as a potential cancer-specific sensitizer to carbon-ion beam therapy
(79) Apr 20, 2017
Hironori YOSHINO (Hirosaki University Graduate School of Health Sciences)
Effects of endoplasmic reticulum stress on apoptosis induction in radioresistant macrophages
(78) Apr 20, 2017
Hironori YOSHINO (Hirosaki University Graduate School of Health Sciences)
Involvement of reactive oxygen species in ionizing radiation–induced upregulation of cell surface Toll-like receptor 2 and 4 expression in human monocytic cells
(77) Mar 28, 2017
Norie KANZAKI (Graduate School of Health Sciences, Okayama University) Analysis of damage in mouse liver from radon, X-ray, or alcohol treatments using a self-organizing map
2016年 Our Research (71)～(76) の投稿はこちらからお読みいただけます
(76) Oct 6, 2016
Reo Etani (Graduate School of Health Sciences, Okayama University)
Difference in the action mechanism of radon inhalation and radon hot spring water drinking in suppression of hyperuricemia in mice
(75) Sep 26, 2016
Daisuke Iizuka (Department of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University)
Hepcidin-2 in mouse urine as a candidate radiation-responsive molecule.
(74) Sep 23, 2016
Takahiro KATAOKA (Graduate School of Health Sciences, Okayama University)
Activation of antioxidative functions by radon inhalation enhances the mitigation effects of pregabalin on chronic constriction injury-induced neuropathic pain in mice
(73) Sep 23, 2016
Nobuyuki HAMADA (Central Research Institute of Electric Power Industry)
Ionizing radiation induced cataracts: Recent biological and mechanistic developments and perspectives for future research
(72) Sep 23, 2016
Nobuyuki HAMADA (Central Research Institute of Electric Power Industry)
Cataractogenesis following high-LET radiation exposure
(71) Aug 29, 2016
Mikio Shimada (Tokyo Institute of Technology)
Induction of Excess Centrosomes in Neural Progenitor Cells during the Development of Radiation-Induced Microcephaly
2015年 Our Research (64)～(70) の投稿はこちらからお読みいただけます
(70) Sep 29, 2015
Yu Abe (Department of Radiation Life Sciences, Fukushima Medical University School of Medicine)
TIncrease in dicentric chromosome formation after a single CT scan in adults
(69) Sep 16, 2015
Huizi LI (National Institute of Radiological Sciences and Graduate School of Medical and Pharmaceutical Sciences, Chiba University)
Transcriptomic signatures of Auger electron radioimmunotherapy using unclear targeted 111In-trastuzumab for potential combination therapies
(68) Sep 15, 2015
Kiichi KAMiNAGA (Graduate School of Science and Engineering, Ibaraki University and Japan Atomic Energy Agency)
VISUALIZATION OF CELL CYCLE MODIFICATION BY X-IRRADIATION IN SINGLE HELA CELLS USING FLUORESCENT UBIQUITINATION-BASED CELL CYCLE INDICATOR
(67) Sep 2, 2015
Nobuyuki HAMADA (International Commission on Radiological Protection)
Dose and dose-rate effects of ionizing radiation: a discussion in the light of radiological protection
(66) Aug 27, 2015
Nobuyuki HAMADA (Central Research Institute of Electric Power Industry)
Role of carcinogenesis related mechanisms in cataractogenesis and its implications for ionizing radiation cataractogenesis
(65) Aug 25, 2015
Mikio SHIMADA (Tokyo Institute of Technology, St. Jude Children’s Research Hospital)
Polynucleotide kinase–phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability
(64) Nov 11, 2014
Takaaki YASUHARA (Graduate School of Medicine, The University of Tokyo)
Rad54B serves as a scaffold in the DNA damage response that limits checkpoint
2014年 Our Research (58)～(63) の投稿はこちらからお読みいただけます
(63) Sept 16, 2014
Nobuyuki HAMADA (Central Research Institute of Electric Power Industry)
Emerging issues in radiogenic cataracts and cardiovascular disease.
(62) Sept 15, 2014
Takahiro KATAOKA (Graduate School of Health Sciences, Okayama University)
Effects of naturally occurring radioactive material (NORM) on reactive oxygen species induced damage.
(61) Sept 15, 2014
Hironori YOSHINO (Hirosaki University Graduate School of Health Sciences)
Ionizing radiation affects the expression of Toll-like receptors 2 and 4 in human monocytic cells through c-Jun N-terminal kinase activation
(60) Aug 9, 2014
Nobuyuki HAMADA (Central Research Institute of Electric Power Industry)
Classification of radiation effects for dose limitation purposes: history, current situation and future prospects.
(59) May 21, 2014
Nobuyuki HAMADA (Central Research Institute of Electric Power Industry)
What are the intracellular targets and intratissue target cells for radiation effects?
(58) May 19, 2014
Yuki FUJIMICHI (Central Research Institute of Electric Power Industry)
Ionizing irradiation not only inactivates clonogenic potential in primary normal human diploid lens epithelial cells but also stimulates cell proliferation in a subset of this population.
2013年 Our Research (53)～(57) の投稿はこちらからお読みいただけます
(57) Sep 25, 2013
Takahiro Kataoka (Okayama University)
Comparative Study on the Inhibitory Effects of Antioxidant Vitamins and Radon on Carbon Tetrachloride-induced Hepatic and Renal Damage.
(56) Sep 12, 2013
Yuichiro Saito (Radiation Biology Center, Kyoto University)
The proteasome factor Bag101 binds to Rad22 and suppresses homologous recombination.
(55) Sep 7, 2013
Hironobu Yasui (Hokkaido University)
The prospective application of a hypoxic radiosensitizer, doranidazole to rat intracranial glioblastoma with blood brain barrier disruption.
(54) Sep 2, 2013
Tatsuhiko Imaoka (National Institute of Radiological Sciences)
Complex interactions between ionizing radiation and cancer-initiating chemicals on rat mammary carcinogenesis.
(53) Jun 10, 2013
Shigeyoshi Saito (Osaka University) Manganese-Enhanced MRI Reveals Early-Phase Radiation-Induced Cell Alterations In Vivo.
2012年 Our Research (46)～(52) の投稿はこちらからお読みいただけます
(52) Aug 23, 2012
Yi Shang (National Institute of Radiological Sciences)
Interleukin-9 Receptor Gene is Transcriptionally Regulated by Nucleolin in T-Cell Lymphoma Cells.
(51) Aug 23, 2012
Hironori YOSHINO (Hirosaki University Graduate School of Health Sciences)
Impairment of mature dendritic cells derived from X-irradiated human monocytes depends on the type of maturation stimulus used.
(50) Aug 23, 2012.Shinobu Hirano (National Institute of Radiological Sciences, Juntendo University)
Ikaros is a critical target during simultaneous exposure to X-rays and N-ethyl-N-nitrosourea in mouse T-cell lymphomagenesis.
(49) Apr 2, 2012
Takahiro KATAOKA (Graduate School of Health Sciences, Okayama University)
Protective Effects of Radon Inhalation on Carrageenan-Induced Inflammatory Paw Edema in Mice.
(48) Feb 15, 2012
Takahiro KATAOKA (Graduate School of Health Sciences, Okayama University)
Review Article: Activation of Biodefense System by Low-Dose Irradiation or Radon Inhalation and Its Applicable Possibility for Treatment of Diabetes and Hepatopathy.
(47) Feb 15, 2012
Takahiro KATAOKA (Graduate School of Health Sciences, Okayama University)
Radon Inhalation Protects Mice from Carbon-Tetrachloride-Induced Hepatic and Renal Damage.
(46) Feb 15, 2012
Takahiro KATAOKA (Graduate School of Health Sciences, Okayama University)
Study of the Response of Superoxide Dismutase in Mouse Organs to Radon using a New Large-Scale Facility for Exposing Small Animals to Radon.
2011年 Our Research (36)～(45) の投稿はこちらからお読みいただけます
(45) Oct 28, 2011
Tatsuhiko IMAOKA (National Institute of Radiological Sciences)
Childhood and adulthood radiation exposure induces distinct types of rat mammary carcinoma
(44) Oct 20, 2011
Tokuhisa HIROUCHI (Institute for Environmental Sciences)
Whether radiation promotes spontaneous leukemia or induces unusual leukemia?
(43) Oct 13, 2011
Hisakatsu NAWATA (Research Reactor Institute, Kyoto University)
Dysregulation of Gene Expression in the Artificial Human Trisomy Cells of Chromosome 8 Associated with Transformed Cell Phenotypes
(42) Sep 7, 2011
Mikio SHIMADA (Radiation Biology Center, Kyoto University)
Genistein, isoflavonoids in soybeans, prevents the formation of excess radiation-induced centrosomes via p21 up-regulation
(41) Jul 26, 2011
Takahiro KATAOKA (Graduate School of Health Science, Okayama university)
Studies on possibility for alleviation of lifestyle diseases by low-dose irradiation or radon inhalation
(40) Jun 11, 2011
Nobuyuki HAMADA (Central Research Institute of Electric Power Industry)
Special issue on non-targeted radiation effects
(39) Jun 6, 2011
Kyosuke NAKAMURA (Radiation Biology Center, Kyoto University)
Regulation of Homologous Recombination by RNF20-Dependent H2B Ubiquitination
(38) Jun 6, 2011
Mikio SHIMADA (Radiation Biology Center, Kyoto University)
The potential roles of DNA repair proteins in centrosome maintentance
(37) Apr 28, 2011
Shigeyoshi SAITO (National Institute of Radiological Sciences)
Quantitative assessment of central nervous system disorder induced by prenatal X‐ray exposure using diffusion and manganese‐enhanced MRI
(36) Jan 15, 2011
Shigeyoshi SAITO (National Institute of Radiological Sciences)
Quantitative and Noninvasive Assessment of Prenatal X-Ray-Induced CNS Abnormalities Using Magnetic Resonance Imaging
2010年 Our Research (26)～(35) の投稿はこちらからお読みいただけます
(35) Oct 24, 2010
Yoshihiro FUJII (University of Tokyo)
Ascorbic acid gives different protective effects in human cells exposed to X-rays and heavy ions
(34) Oct 24, 2010
Yoshihiro FUJII (University of Tokyo)
p53 independent radio-sensitization of human lymphoblastoid cell lines by Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin
(33) Sep 26, 2010
Yuka ISHIDA (National Institute of Radiological Sciences)
Genomic and gene expression signatures of radiation in medulloblastomas after low-dose irradiation in Ptch1 heterozygous mice
(32) Sep 26, 2010
Akinori MORITA (Faculty of Science and Technology, Tokyo University of Science)
Sodium orthovanadate is a bifunctional inhibitor of transcription-dependent and -independent p53-mediated apoptosis
(31) Sep 26, 2010
Daisuke IIZUKA (Research Institute for Radiation Biology and Medicine, Hiroshima University)
DNA copy number aberrations and disruption of the p16Ink4a/Rb pathway in radiation-induced and spontaneous rat mammary carcinomas
(30) Sep 26, 2010
Mikio SHIMADA (Radiation Biology Center, Kyoto University)
Differential role of repair proteins, BRCA1/NBS1 and Ku70/DNA-PKcs, in radiation-induced centrosome over-duplication
(29) Aug 12, 2010
Yoshikazu KUWAHARA (Institute of Development, Aging and Cancer, Tohoku University)
The modified high-density survival assay is the useful tool to predict the effectiveness of fractionated radiation exposure
(28) Aug 1, 2010
Yuichiro YOKOTA (Japan Atomic Energy Agency)
Evidence for radiation-induced genomic instability in plant cells
(27) Jul 29, 2010
Nobuyuki HAMADA (Central Research Institute of Electric Power Industry)
Recent progress in the biology of heavy-ion cancer therapy: a review
(26) Apr 16, 2010
Kensuke OTSUKA (Central Research Institute of Electric Power Industry)
Regeneration capability of hematopoietic stem cells after radiation exposure
2009年 Our Research (16)～(25) の投稿はこちらからお読みいただけます
(25) Nov 19, 2009
Takahiro KATAOKA (Graduate School of Health Sciences, Okayama Universty)
Study on Active Changes in Biological Function on Mouse Liver Graft in Cold Storage after Low-dose X -irradiation
(24) July 30, 2009
Mikio SHIMADA (Radiation Biology Center, Kyoto University)
Emerging Connection Between Centrosome and DNA Repair Machinery
(23) June 17, 2009
Yi SHANG (National Institute of Radiological Sciences)
A new link between radiation-induced lymphomagenesis and its genetic susceptibility
(22) June 17, 2009
Kazuhiro DAINO (National Institute of Radiological Sciences)
Gene expression profiling of alpha-radiation-induced rat osteosarcomas
(21) June 12, 2009
Tatsuhiko IMAOKA (National Institute of Radiological Sciences)
Experimental studies on radiation-induced mammary carcinogenesis: a review
(20) June 2, 2009
Kentaro ARIYOSHI (National Institute of Radiological Sciences)
Introduction of a Normal Human Chromosome 8 Corrects Abnormal Phenotypes of Werner Syndrome Cells Immortalized by Expressing an hTERT Gene
(19) June 1, 2009
Mikio SHIMADA (Radiation Biology Center, Kyoto University)
Inactivation of the Nijmegen Breakage Syndrome gene leads to excess centrosome duplication via the ATR/BRCA1 pathway
(18) Apr 14, 2009
Genro KASHINO (Research Reactor Institute, Kyoto University)
Induction of DNA double-strand breaks and cellular migration through bystander effects in cells irradiated with the slit-type microplanar beam of the spring-8 synchrotron
(17) Feb 24, 2009
Hiroshi Harada (Kyoto Univ. Grad. Sch. Med)
Optimization of Radiation and HIF-1-targeting Therapys
(16) Feb 24, 2009
Hiroshi Harada (Kyoto Univ. Grad. Sch. Med)
Mechanism of HIF-1a expression in irradiated solid tumors
2008年 Our Research (1)～(15) の投稿はこちらからお読みいただけます
(15) Sep 7, 2008
Kenshuke Otsuka (Ctr. Res. Inst. Elect. Pow. Indust)
A possible mechanism of whole-body radioadaptive response
(14) Sep 7, 2008
Mitsuaki Ojima (Oita Univ. Nurs. Health Sci)
DNA double-strand breaks induced by very low X-ray doses are largely due to bystander effects
(13) Sep 1, 2008
Nobuyuki Hamada (Gunma Univ. Grad. Sch. Med)
A review of the biological action of heavy-ion radiation
(12) Aug 22, 2008
Nobuyuki Hamada (Gunma Univ. Grad. Sch. Med)
Sensitization of tumor cells to heavy-ion radiation
(11) July 16, 2008
Hiroshi Harada (Kyoto Univ. Grad. Sch. Med)
Dynamics of HIF-1-active regions during tumor progression
(10) June 26, 2008
Hiroshi Harada (Kyoto Univ. Grad. Sch. Med)
HIF-1-active region; a target to overcome the radioresistance of tumors
(9) June 26, 2008
Hiroshi Harada (Kyoto Univ. Grad. Sch. Med)
Hypoxia-targeting gene therapy improves the control of tumour growth after radiotherapy
(8) June 26, 2008
Hiroshi Harada (Kyoto Univ. Grad. Sch. Med)
Optical imaging of intratumoral HIF-1 activity in real-time
(7) May 21, 2008
Tatsuhiko Imaoka (National Institute of Radiological Sciences)
Distinguishing which tumor is radiation-induced
(6) Apr 30, 2008
Nobuyuki Hamada (Gunma Univ. Grad. Sch. Med)
The bystander effect of heavy-ion radiation
(5) Apr 17, 2008
Yoshitaka Matsumoto (Natl. Inst. Radiol. Sci)
Difference of gene expression profiles in human malignant melanoma cell lines between carbon-ion and X-ray irradiations
(4) Mar 26, 2008
Nobuyuki Hamada (Gunma Univ. Grad. Sch. Med)
Genomic instability induced by heavy-ion radiation
(3) Mar 6, 2008
Motohiro Yamauchi (Grad. Sch. Biomed. Sci., Nagasaki Univ.)
Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling
(2) Mar 1, 2008
Nobuyuki Hamada (Gunma Univ. Grad. Sch. Med)
Overcoming tumor radioresistance with heavy-ion radiation
(1) Mar 1, 2008
Tatsuhiko Imaoka (National Institute of Radiological Sciences)
Heavy ion RBE on cancer induction